Marginalization and Violence

Studies on random violence and terrorist acts have found that individuals and groups who are marginalized may be more at risk. Persecution and humiliation and child trauma or neglect was more common in the history of people arrested for a violent crime. The recent death of a peaceful protester in Charlottesville is tragic for the family and community, and the nation. (bloomberg.com/2017-08-14)

We are becoming even more divided since the difficult campaign season but marginalizing young adults may just lead to more violence. A group that has appeared to be supportive of or producing the Nazi themed memes  has a petition up to help save them from oppression, whether it might be satire about saving Pakistan is unclear. (change.org/p/the-recognition-and-freedom-of-the-kekistani-people)

Young adults who are just looking for recognition and freedom from “normies” may need more variety of role models to follow. When “normal” society is the bad guy and Trump is the savior figure in the artwork – we all have a problem.

There are a few articles on my website about Zionism and World War II but the information is not in support of Hitler. Anti-Zionist at the time of World War II included Jewish people, such as Albert Einstein. There was collusion between Hitler and the Zionists at the time which may have left more of the non-Zionists Jews at risk for the concentration camps while a few left early for Palestine and they were allowed to take their possessions.  It all may involve banking and the national monetary system that Germany put in place after WWI cost them a large amount in reparations. History is complicated and the winners write the books.

I’ve been working on a health information website, a directory of links to other resources with narrative about their value. It started out as an example of a policy manual for preventing harassment and discrimination in the workplace.

Violence is bad, um’kay.” (A paraphrase of a line from Southpark.)

The footnotes aren’t renumbered for this yet, either. but here is a section regarding random violence and humiliation of others. When one is singled out for persecution it is warning all the others in the group and other marginalized groups, that if they aren’t careful then they could get the same treatment – so follow the group’s expectations – their norms. As a medical marijuana patient I’ve been in a marginalized group and the expectation has been to quit being an addict and take part in the business world and social community. I can’t. I’ve tried many times and my health keeps getting worse when I try.  It’s proven to me even more how important it is for my health.

Policy manuals can set consistent standards and be shared quickly. My own role as an administrator included many of them because I worked in a rural area with a small caseload and small budget for staff. As the main Program Coordinator I was responsible for several and then I also had the roles of “Nutrition Education Coordinator,” “Breastfeeding Coordinator,” and “Outreach Coordinator” – it doesn’t fit on a resume line let alone look good in a Human Resources interview. Each role had manuals to keep up to date, and it being a large rural area, I had four sets to keep up to date, one for each of four locations that the same few staff traveled too. Seven years later can I remember them? The names aren’t right, but, 1. the main State/Federal Policy Manual; 2. the Local Agency Policy and Procedures Manual (I had to write that one with our local methods for required policies and procedures); 3. AnthropometricLab & Clinic Standards Manual; 4. Civil Rights Training Manual; 5. Outreach Manual; 6. Nutrition Education Lesson Plan Manual with examples of all the handouts used, this was mostly original writing also, with some lessons and handouts from the state or other local agencies; 7. the Breastfeeding Manual; 8. the Coupon Inventory Log; and 9. the Equipment Inventory.

I loved my job – what I really did was measure babies and children, poke fingers for iron lab tests, assess nutrition, and income and social needs, as well, and provide education and counseling guidance as needed and enter it in the computer and print out food coupons – with few staff available I worked clinics by myself sometimes or with one other person to help. Updating policy manuals or even reading them was spare time work for at home in the evening, unpaid, or occasionally approved overtime on a weekend for an end of the year report or audit. With few staff it is difficult to make time during a work week for much besides the ten to forty clients I might have seen in a day.

The following is an excerpt from a book about policy manuals – exciting:

9.4: “Running amok,” “going postal,” or “a red stapler” moment.

Creating a pleasant work atmosphere where people feel safe from unfair persecution or humiliation may help prevent sudden violence where people who had seemed like quiet average people snap and try to harm others.

The sudden outburst of violence is not that common and is not about a serial killer who is concealing themselves as average among peers, or the manipulative and charming boss with a narcissistic, sociopathic, or psychopathic side. A random violent outburst more likely might be the hard worker who finally reached a “camel straw” moment – the proverbial final straw added to a load that makes the already overloaded camel’s burden too heavy for it to carry any further.

Verbal and physical intimidation are more common problems in the workplace; and not reporting problems is also common. When is problem behavior serious? Or when is joking and teasing and pranks approaching harassment?

  • More information and guidance about workplace violence, and examples of common situations in Canadian workplaces is available at violenceautravail.ca/Understanding violence.  The site includes a list of “Examples of Workplace Violence:  being threatened with death or injury; getting hit or pushed; having an object thrown at us; being subjected to sexual touching and sexual assault; being scratching or pinched; being spat at; being yelled at; receiving threatening messages or emails; being ridiculed or humiliated; being threatened physically (for example, being shown a fist); having our property damaged. (9.105)

Labeling situations as serious and reportable may help an employee see that what they are experiencing is “bad enough,” and that they should seek help before anything “really serious” happens.

Labeling emotions can help to recognize when they are starting to build in one self or others. Unrecognized emotions may be more difficult to control because they are unrecognized but are uncomfortable and may lead to agitation and gradually build to more intense out of control anger or fear.

Running amok” is an older term and “going postal,” is a newer term for sudden violence. A “red stapler” moment is a reference to a movie from the 90’s that became an instant classic among disgruntled workers everywhere: Office Space.

  • If you happened to missed it, then if you would just go watch Office Space, “That would be great.” (9.79)
  • Or go read this article about it: 20 Things You Might Not Know About Office Space (9.80)

The movie Office Space shows all the “do not do this to your employees” bad boss examples to avoid following. Don’t be left holding only a stapler, plan ahead and give everyone their own. Fair treatment and a sense of autonomy, a right to some control over one’s work, are important for employees in addition to earning a fair paycheck. Threatening job loss or other retaliations can leave workers feeling trapped and hopeless because they may need that paycheck even if it isn’t fair.

9.5: “Amok” was a medical condition during stressful times.

Research has found that during stressful times, whether due to economic or environmental reasons, people are more likely to act out verbally or physically against people who are not of their same ethnic group. (9.41) During times of stress, violence against women is also more common, particularly against women who are suspected to be sexually active or to have been unfaithful in a relationship. (9.43) Other research has found that the rate of violent crime is associated with the rate of infection in the population. Research into group and individual behavior suggests that the rate of infectious disease in a group is significantly associated with the rate of violent and property crime and with the rate of violent crime against strangers. (9.41)

It is unclear from epidemiology studies whether an association is causal or correlated, but if health is associated with less violence, it seems like a reasonable goal to promote health and try to prevent infectious disease.

Some types of infectious disease can directly lead to symptoms of increased irritability or rage and historically, and times of environmental or economic stress have been linked to a medical condition that was called “amok” where a previously healthy person suddenly started killing or assaulting people randomly. Historically a condition known as amok was first described in 1893 where an individual suddenly acted violently and then would forget the manic episode. Descriptions of the disorder were recorded by the British medical superintendent of the Government Asylum in Singapore. Increases in cases of amok were more associated with “times of social tension or impending disaster.”

The term fell out of use as a medical diagnosis but became commonly used in the phrase “running amok” to describe anyone who was acting unusually out of control. 99.42) Gun violence in modern times has involved racist xenophobia or religious ideology in many cases (9.53, 9.54, 9.56), it can also involve copycat reactions to news coverage of other violent offenders, (9.55), and in a few cases may have involved a shooter who claimed to have amnesia of the event afterwards. (9.44, 9.45)

Is “amok” a real condition that needs a more modern name? Controlling guns doesn’t control violence with knives or vehicles or explosives or with poisons. Promoting health might help more individuals control themselves.

Negligence can also be lethal.

Promoting compassion for others rather than supporting persecution and humiliation of those who are different is necessary. The young learn by observing the way others act and how they treat each other. Teaching compassion or another topic is easier with demonstration than discussion. Police brutality that goes unpunished teaches the wrong message that persecution and humiliation of some types of people is okay when it is done by other types of people. Recently teens filmed a man while he drowned and the group’s laughing and taunting was caught on the audio. The teens never reported the drowning and the man’s body was only found after a missing person’s report was filed. The video later became available and legally it has been found to fall into a loophole in the state’s laws. There is no legal requirement to help a person who is in danger in that state. (9.100)

Divisive politics and economic hardship can lead to more focus being placed on differences in religion or culture, sexual orientation or gender, between oneself and others but it doesn’t have to. Being civilized can mean recognizing those differences and valuing and seeking to understand them better instead of fearing or mistreating those who are different from oneself.

  • TJ Brown suggests how in a section “Fight for a More Civilized Bigotry,” (pg 14) from a longer article: FEE’s Guide to Keeping Friends Despite Political Differences: How to Have Opinions and Friends (at the Same Time!), fee.org (9.106)

9.6: Gratitude and friendship boost dopamine, so does shaming.

Shaming others, reminding them of guilt, can cause an increase of dopamine in the brain of the person doing the shaming. However a compassionate exchange with a friend or acquaintance can also boost dopamine, and so can reading new and interesting information. Listening to music and enjoying good food can also. There are many positive ways to boost dopamine besides shaming others, such as being grateful for others’ diverse skills and unique backgrounds.

Shaming others may be a natural instinct to promote one’s own morality by making it clear one is not in support of the topic or person being shamed, (9.21), or it may derive from a sense of guilt about the situation or person being shamed. (9.22)

Being fair in the first place would leave less to feel guilty about, accepting each other for our differences as well as our similarities might also.

Shaming others, purposely humiliating them, can also be a form of control or intimidation to show power over another person or group of people. Shaming one member of a group can serve to humiliate and control the group. Less equal societies, with a group of wealthy elite at the top, may be more likely to use humiliation as a control tactic. (9.81) Human sacrifice in ancient cultures was found in a recent anthropology study to be more common in societies that also had greater inequality between the rich and poor. (9.82)  However, does shaming work as a form of social control to effectively promote changed behavior in the person being shamed?

The answer is no – or at least not effectively and consistently when it comes to alcohol abuse. Research with reality shows focused on alcohol addiction and recovery have found that alcoholism or relapse were still likely to occur even after public shaming. (9.156)

“The results add to a body of literature suggesting that widely used shaming and humiliating methods of treating alcohol and other drug problems — such as those seen on shows like Celebrity Rehab — are not only ineffective but also may be counterproductive.” (9.156)

“Guilt” is a noun referring to the feeling one feels oneself over an error or misdeed, while “shame” can be used as a noun it is more typically used as a verb, “to shame.” Others shame the one who is guilty or believed to be guilty of something the group disapproves of. Other studies with alcohol counseling individually also found that shaming tactics did not effectively help individuals stop abusing alcohol. (9.156)

Studies of serial killers and other types of violent offenders found an association with early childhood abuse. Rejection by a parent or other important person in their life was found to have occurred in the early lives of 48% of a group of 62 serial killers in the study. Other types of physical, sexual or emotional abuse such as humiliation have also been associated with violent offenders, and early adoptions, neglect, or abandonment in early childhood have been associated with violent crime. (9.63)

In a study that included over 1000 violent offenders, shame and humiliation were found to be a common factor; violence was an attempt to restore a sense of pride or self-worth: “In the work, “Shame, Guilt, and Violence,” qualitative data from over 1,000 institutionalized offenders were gathered and analyzed over the course of four decades. According to Gilligan, self-conscious feelings of shame and a deteriorated sense of self-worth are the causal factors underlying violence; humiliation, Gilligan argues, compromises one’s identity, i.e. the way one sees oneself, and leads to feelings conceptualized as a loss of cohesion of the self, or a conceptual death of the self. This leads one to become violent in order to restore pride, or a sense of self-worth (Gilligan, 2003).”  Overcrowding and economic job stress, which leads to lack of parental time, are factors thought to be involved in the number of young men in gangs who may join them seeking the nurturing that was missing at an empty childhood home. (9.83)

If someone at work has a favorite stapler, maybe just let them enjoy it in peace instead of teasing them about it – and maybe get one of your own to find out what the appeal might be. The topic of shame and shaming is continued in the next section, and a therapy method for individuals who suffer from excessive guilt and a tendency to self-shame (9.158) is discussed in more detail.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Is it Addiction or Starvation?

1. Talk Therapy or “Just say no” can’t help a genetic difference.

Talk therapy is also beneficial but can not “cure” a biological difference in metabolism.
  • Looking up the definition of the word “disease” suggests that a genetic difference affecting a body wide receptor system might fit the term “body disease.” “Disease: a disorder of structure or function in a human, animal, or plant, especially one that produces specific signs or symptoms or that affects a specific location and is not simply a direct result of physical injury.” – Oxford Dictionaries (I.1.disease)
Redefining the neurobiological underpinnings and genetic risks of the behavior we call addiction could lead to more targeted help for the sufferers of addiction rather than continuing to treat them primarily by focusing on a discussion of their difficulties with motivation or impulse control.
The Endogenous Cannabinoid System holds answers.
Background information:
  • Endogenous refers to something that can be made internally by our body rather than a chemical that is needed to be obtained from an external source on a daily or semi-regular basis. An example such as oxygen from the air we breathe is needed within every few minutes or cellular damage can start to occur; or trace nutrients such as essential fats or fat soluble vitamins may not be needed as often because they can be stored in the fat and membranes of the body. They may only need to be consumed in the diet every few days or weeks without resulting in negative health effects. The body can store extra vitamin D during summer months that can last most of the winter but does start to run out by springtime.
A person with a metabolic difference due to genetics, chronic illness, or the standard changes associated with aging may need an external source of nutrients that other people of average health would be able to make internally – “endogenously.”
  • Cannabinoids are a type of chemical called phospholipids which are formed from a lipid, a type of fat, and the mineral phosphorus.
I have a genetic difference in my ability to phosphorylate (I.2.wikigenes.BHMT) so that I am unable to make phospholiids endogenously and I have found that having an external source of cannabinoids in my diet every day helps my chronic illness conditions and improves my muscle and nerve control. I am registered as a Medical Marijuana patient in a state where it has been legalized for medical use.
     Some of my symptoms that are relieved by the herbal medicine have been troubling me since I was an infant. I had severe eczema throughout my childhood and severe congestion. Rarely could I breathe through both nostrils and nosebleeds were also common. The enzyme the BHMT gene produces when functioning incorrectly is associated with a risk for vascular problems – ie nosebleeds or easy bruising or spider veins or all of them.
     The protein that the gene normally produces is necessary in Glycerophospholipid biosynthesis, metabolism , and Phospholipid metabolism, (so a double mutation in this gene may make it difficult for me to make phospholipids endogenously), among 17 pathways in all – that is an important enzyme: (I.6.genecards.BHMT) And the CDK-mediated phosphorylation and removal of Cdc6 SuperPath involves 97 other pathways which include a Calcium2+ pathway and a Parkinsons Disease pathway and creatine metabolism (important for muscles) and synthesis of DNA and many other metabolic paths/chains of chemical events : (I.7.genecards.phosphorylation)
  • Phospholipids are found in human breast milk and helps stimulate the infant’s appetite and helps support adequate weight gain. The cannabinoids and phospholipid group perform two main functions – they are flexible and form a significant part of membrane walls, like building blocks or bricks; they can also be released from the membrane and act as messenger chemicals that can activate other systems or be modified slightly to become a different type of messenger chemical called eicosanoids.
  • Eicosanoids include the leukotrienes: Santa Cruz Biotechnology,(I.8.scbt.com)

2. It might be motivating to learn of an underlying cause to cravings.

It might help a person to learn that for a person with a genetic difference, difficulties with motivation or impulse control are likely due to an underlying deficiency of a substance they are missing, which would likely have helped them have better impulse control and to not have cravings for substances.
Someone without the genetic difference would be making the substances internally which would help them have good impulse control and not crave substances.
     Helping the person with substance abuse problems to find approved external sources of the substance (cannabinoids) seems like it would be more helpful and potentially more motivating for them to be able to view themselves as a worthwhile person with special dietary needs rather than as an unmotivated drug addict who just doesn’t try hard enough to change.
     Substance abusers likely quit using and relapsed again more times than anyone cares to count. every single time a chronic user runs out of their substance of choice they are “quitting” until they get more.
     Do you blame a hungry person for eating breakfast in the morning? Should a person just “quit eating” if they have an overeating disorder? Answer: No.
  • Cannabinoids might help some types of eating disorders and some types of drug or alcohol addictions by providing an essential nutrient that the person might not be able to make.
  • If the body can’t make an important substance or convert substances into active forms then it becomes an essential nutrient – essential for that specific person’s daily diet.

3. Genetics of the cannabinoid system and binge eating disorder, alcohol abuse and drug addiction.

“It is important to note that, as with alcohol, marijuana, and heroin, a human genetic variant of the cannabinoid CB1 receptor gene CNR1 has been associated with susceptibility to cocaine and amphetamine dependence (Ballon et al. 2006, Comings et al. 1997; Zhang et al. 2004).
  • Behavioral Neurobiology of the Endocannabinoid System; Ch.13: Drug Addiction, (page 334, I.9.Searchworks)
Endocannabinoids: The Brain and Body’s Marijuana and Beyond is a reference textbook available online as a pdf. (I.10.Endo.pdf)  It includes information regarding the genetic differences known to be associated with binge eating disorder and other drug addictions affected by rimonabant, a chemical which inhibits the endogenous cannabinoid system. Use of rimonabant affected craving for food/sucrose and alcohol in animal research, and it was found to reduce rewarding effects of morphine/opioids, amphetamine, cocaine and diazepam in other studies.
  • Rimonabant is not in use for drug addictions because it is associated with a significantly increased risk for suicide. This is an important point to note – blocking the endogenous cannabinoid system is associated with a significant risk for suicide.
The problem with addiction to some substances or to eating excess food for some cases of over eating disorders is an underlying inability to make the cannabinoids but a remaining need for them and a hunger, an urge for “something,” something that is unknown however. And what people choose to consume in order to try to quench that unknown hunger varies from food and alcohol, to the rest of the drugs that are commonly abused.
     Dietary sources are needed instead. However our food supply has limited sources. Vine ripened produce or lemon oil, rich in aroma, are examples of a food containing cannabinoids or a similar group of aromatic and medicinal phytochemicals called terpenes. Chocolate and the herb rosemary are two other food sources. The spices cardamom, cloves, and nutmeg are also sources. Non-euphoric cannabinoids also exist and may have medicinal benefits depending on the patient’s condition. Copaiba oil is a food grade essential oil that can have non-euphoric cannabinoid content with medicinal benefits.
     Wouldn’t it be nicer to tell starving people that they are starving rather than that they are poorly motivated?
  • For more information regarding binge eating disorder, drug addiction and rimonabant: See Ch.3: Endocannabinoid Receptor Genetics and Marijuana Use, (p72-73 & 91, I.10.Endo.pdf) and Ch.13: Behavioral Effects of Endocannabinoids, mentions that research with rimonabant has helped show excessive alcohol drinking behavior and development of alcoholism may be related to genetic differences in the CB1 receptors. (p319, I.10.Endo.pdf)
  • Impulse control deficits may involve the cannabinoid system: See Ch.13: Behavioral Effects of Endocannabinoids, (pp325-330, I.10.Endocannabinoids.Full Text.pdf).
  • Schizophrenia may be related to a deficiency in the cannabinoid receptors themselves rather than being due to a deficiency in cannabinoids: See Ch.15, Neuropsychiatry: Schizophrenia, Depression, and Anxiety,; of the book Endocannabinoids: The Brain and Body’s Marijuana and Beyond: (p378, I.10.Endocannabinoids.Full Text.pdf)
More recently a gene has been identified in binge eating disorder, the gene for the cytoplasmic FMR1-interacting protein 2 (CYFIP2). (I.11.sciencedaily) The gene has a number of known variations and has allso been associated with Fragile X, an autism like condition, ADHD, autism, obsessive-compulsive behavior, and Prader-Willi Syndrome.. (I.12.ncbi.FragileX)
     The enzyme the gene CYFIP2 produces when functioning normally is involved in many metabolic pathways in the body including one that plays a role in myelination of nerve cells and one in phospholipid metabolism. (I.13.reuters) (I.14.genecards.CYFIP2)
     So an external source of cannabinoids might help a person with a problem in their CYFIP2 gene to have normal appetite control and also to protect their nerves from multiple sclerosis – which causes degeneration of myelin.  Myelin is similar to the lipid part of some of the phospholipids of the endogenous cannabinoid system. Multiple sclerosis has been associated with social anxiety and eating disorders (I.15.omicsgroup) which are also conditions associated with gene differences in the cannabinoid system. Myelin is made with sphingomyelin which is made of sphingolipids. (I.16.sphingolipids) Easy right? (I.17.mpcfaculty.lipids) Even easier – coconut oil is about 50% phospholipids and is a good source of sphingolipids. (I.18.coconut)
    I don’t know if I have any differences in my CYFIP2 gene; it was not one of the 30 genes that were included in the Nutrigenomic Screening I had done for my personal use for the “purposes of research.” Genetic screening is only used for certain conditions in standard health care currently and some types of health care claims can not be made by practitioners about genetic screening for other conditions – no guarantees in life or lab tests. The screening I had was designed to test genes commonly found to have differences associated with autism. (I.33.Nutrigenomic Screening) (p22, I.34.example of the genetic screening I had)
     I have a genetic difference in my ability to phosphorylate (I.2.wikigenes.BHMT) The gene I have a double malfunction in, BHMT, is also associated with multiple sclerosis except it seems to be with an over activity rather than too little function. Methionine and homocysteine metabolism and vitamin B12 may be involved. (I.19.BMHT.MS) Hypothyroidism may be associated with over expression of this gene: (I.20.wikigenes)
     The enzyme BHMT/1 (Call – T), Betaine-homocysteine methyltransferase (BHMT), in normal health helps produce the amino acids methionine and Dimethylglycine (DMG).
     DMG has been found helpful in ADHD, autism, allergies, alcoholism drug addiction, and chronic fatigue syndrome among other chronic issues. Methionine has been found helpful in treating depression, allergies, alcoholism and schizophrenia among other chronic issues. Since learning of the difference in my genetics I have been taking the two amino acids in a powder form that I add to a glass of water. It doesn’t taste good but it leaves me feeling more energetic and with a more positive mood.
     What it tasted most like was a tart red wine and the nutrient content of red wine does contain free amino acids, so someone with a problem with the BHMT gene may have problems with unidentified cravings that wine seem to help. While I did love red wine, it didn’t love me. It was one of the first triggers for severe migraines that I identified and started avoiding. A painkiller did help with migraine pain somewhat but zero time spent with a migraine is my goal.
     I found based on the information that is available regarding dose, that a half teaspoon of each of the amino acid powders helped my mood without causing such an energy boost that it caused an increased heart rate or prevented me from going to sleep. I tried one teaspoon of each initially and found that it was too much of an energy boost. Both amino acids can act as activating chemicals within the brain.
     I have early symptoms of neuropathy, I would rather prevent multiple sclerosis than to learn more about it first hand. Taking the supplemental methionine may be helping my body do what it needs to do to prevent an autoimmune breakdown of my myelin.

4. Sometimes people are wrong – Nixon was wrong.

If the good people, in their wisdom, shall see fit to keep me in the background, I have been too familiar with disappointments to be very much chagrined.” – Abraham Lincoln (1809-1894), (p 634, I.23)
Hemp fiber was essential for rope and strong fabric. Thomas Jefferson grew hemp and is said to have smoked it too. It is time to stop being disappointed in loved ones who are likely suffering from a metabolic deficiency that leaves them susceptible to substance abuse or overeating and instead start accepting that they have needs that a person of average health doesn’t have or may not have to the same extent. Many nutrients are needed in a just right amount, not too little or too much.
     Cannabinoids are powerful and can be consumed in excess however it does not have the toxicity and deadliness of many other substances that are abused, including alcohol.
     The American Medical Association has recommended that marijuana be rescheduled as an herb with medicinal benefits. (I.24.AMA resolution) (I.25.veteransformedicalmarijuana)
     Rescheduling marijuana as a medicinal plant would free academic researchers to study its medicinal benefits. As a “Scheduled Substance” currently research studies are only supposed to assess toxicity and rehabilitation areas rather than design experiments assessing the medicinal value. Currently the synthetic form of the main euphoric cannabinoid, THC, is listed at a “safer” level of risk than the marijuana plant itself.
     The synthetic forms can be even more dangerous as they are more concentrated and are in isolation rather than also providing the non-euphoric cannabinoids that are found in most strains of marijuana and which have calming effects. Synthetic THC or THC in excess can cause paranoia and other mood symptoms that would have been unknown to Thomas Jefferson when he enjoyed smoking marijuana that was milder in the amount of THC it likely contained and more likely to be balanced with non-euphoric cannabinoids.
     The problem with black market development of a product is that it is often being designed to maximize the “buzz” or “euphoria” rather than the medicinal or pain killing effects. However, there is not that much “euphoria” felt by the person with chronic illness who is using a larger quantity of marijuana everyday due to an underlying inability to make cannabinoids because a tolerance is built up and they simply need some of the herb or other concentrated sources of cannabinoids every day just to maintain a state of health and function that is a little closer to everyone else’s “normal function“.    

     The person with a chronic need wants an herbal medicine that has a balanced variety of cannabinoids that treats a variety of symptoms, not just the euphoria inducing THC that can lead to overdose symptoms of a racing heart, feeling very chilled, and paranoia or anger combined with extra energy, so manic behavior might be a risk with an overdose reaction. Real lime or lemon juice products that are concentrated rather than being a watery lemonade may help counteract some of the mood changes associated with an overdose of THC. More on lemon oil is included in the next section. 

5. Medical Marijuana helps reduce opioid use, which can save lives.

     We currently have an epidemic of deaths due to opioid medications, prescription and black market drugs. The increase in deaths is due in part to the over prescription of opioid painkillers by the medical community but it is also due to black market substitutes that have been introduced in recent years. One type is particularly potent and is being sold as something else so consumers wouldn’t even know that they were being given a stronger version of an opioid medication than the prescription medication they were told they were purchasing on the black market – key point – don’t buy drugs on the black market because you don’t know what they might contain.
     This likely seems an obvious point which, honestly, even the drug addict knows that but their need is great enough during withdrawal that they may be more likely to take risks.
     Women may be especially at risk for opioid addiction whether it is due to differences in size or physiology is unknown. Addiction to opioids seems to occur for women at lower doses of the medication that were taken for a shorter amount of time than for men who become addicted. Women may be more susceptible to the cravings for the drug. (I.27.jotopr)
     In states with medicinal marijuana sales of painkillers dropped,which would include the opioids. Physicians are not comfortable with the inability to “prescribe” a set dose. “Take two hits and call me in the morning?” was asked in jest or in seriousness by a psychiatry professor, Deepak D’Souza, who also has researched marijuana. (I.28.npr)
     Deaths due to overdoses of opioids have also decreased in those states. (I.29.nbcnews) The cannabinoid and opioid receptor systems may both be involved in the regulation of appetite. Levels of the hormone leptin may be increased in response to CB1 receptors in the hypothalamus. Leptin and other appetite hormones may then “control opioid-regulated feeding…(Verty et al., 2003).” See Ch.13: Behavioral Effects of Endocannabinoids, (p313, I.10.Endocannabinoids.Full Text.pdf).
     Since marijuana use seems to be saving lives and has low toxicity risks, it doesn’t seem like how big a dose is as big a question as how to get a safe reliable supply to more patients in pain. The answer does exist but it is one a physician or psychiatrist is unlikely to like – the dose varies based on the person’s genetics and metabolism, the supply of nutrients available, tolerance, etc.; the answer is “It depends.” But the medication is so safe that worries about “too much” are really unnecessary, except possibly for more concentrated synthetic sources or extracted cannabinoid oil products.
     Signs of “too much” THC or synthetic THC can include a racing heartbeat, which very, very rarely has caused a couple/very few deaths. To the user first experiencing the racing heartbeat of excess THC, it may be frightening and feel like a panic attack. Relax it slows down again and only people with a pre-existing heart condition may be at risk during the time that the heart-rate is rapid.
     So if you have a weak heart – avoid excessive amounts of THC. The rapid heart-rate doesn’t occur at low doses. It may be accompanied a feeling of being chilled, and suddenly needing a jacket. Anxiety or anger may occur with excess THC or synthetic THC or during withdrawal from an excessive amount.
     The aromatic terpenes in citrus oil can have a calming effect if anxiety is a problem after consuming marijuana. Pinene from pistachio nuts may also be helpful, but a glass of lemonade might help the mood more quickly than eating pistachios because they would take longer to digest. (I.26.fastcompany)
     Artificial lemon flavored products wouldn’t help, only real lemon or lime juice products would help calm a mood unsettled by an excess or imbalance of THC. The plant contains many active phytochemicals which can include terpenes and other cannabinoids that are calming to the mood rather than causing euphoria. THC is the only cannabinoid in marijuana that causes euphoria.
     Opioid medications also cause euphoria – so why is one more socially acceptable than the other? Smoking is dirty and smelly and – the easiest way to not overdose.
     Eating products or the concentrated synthetic dose in one single sitting can leave a person feeling symptoms of overdose about one hour later, far too late to stop at half a serving or a small taste to see how you might handle that particular product and/or the strain that was used in it. Different strains of the plant can cause very different symptoms and help different types of symptoms, so the question of “how much” is less significant than which strain to use and the method to use to consume it.
     Smoking provides fairly instant changes to the mood so it is easy to tell if you’re getting more anxious or developing a rapid heart rate. Strains of marijuana can vary a lot, some types may cause the anxiety symptoms, while others would just cause the stereotypical “couchlock” – falling asleep. While setting fire to the couch might be a very real risk, otherwise, no danger other than possibly drooling a little and looking stupid. Looking stupid is better than looking dead from an opioid overdose – in my opinion – and I am a medical marijuana patient who has experienced these symptoms and read research about safe use.

6. Resources for help or just someone to talk to:

  • National Helpline: Substance Abuse and Mental Health Services Administration: “SAMHSA’s National Helpline, 1-800-662-HELP (4357), (also known as the Treatment Referral Routing Service), is a free, confidential, 24/7, 365-day-a-year treatment referral and information service (in English and Spanish) for individuals and families facing mental and/or substance use disorders.” (1.30samhsa.org)
  • Rape, Abuse and Incest National Network, RAINN Hotline: 1-800-656-HOPE, (1.31RAINN.)
  • U.S. National Suicide Prevention Hotline: “Call 1-800-273-8255, Available 24 hours everyday.” (1.32.suicidepreventionlifeline.org)

Help is only helpful when you accept it. Recognizing that you need it is the first step.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Links and References:

(I’ll finish this list later, I’ve learned a lazy editing tactic is to skip the footnote numbers until the final draft is complete.)

  1. Disease,” Oxford Dictionaries (I.1.disease)
  2. BHMT,” wikigenes.org, http://www.wikigenes.org/e/gene/e/635.html (I.wikigenes.BHMT)
  3. Glycerophospholipid biosynthesis,
  4. metabolism ,
  5. Phospholipid metabolism,
  6. (I.6.genecards.BHMT) [http://www.genecards.org/cgi-bin/carddisp.pl?gene=BHMT] (I.6.genecards.BHMT)
  7. (I.7.genecards.phosphorylation) [http://pathcards.genecards.org/card/cdk-mediated_phosphorylation_and_removal_of_cdc6] (I.genecards.phosphorylation)
  8. Leukotriene,” (I.8.scbt.com)
  9. Behavioral Neurobiology of the Endocannabinoid System; Ch.13: Drug Addiction, (page 334, I.9.Searchworks)  Behavioral Neurobiology of the Endocannabinoid System, Editors David Kendall and Stephen Alexander (Springer, 2009, Nottingham, U.K.). (I.Searchworks)
  10. Endocannabinoids: The Brain and Body’s Marijuana and Beyond, (CRC Press, 2006, Boca Raton, FL), Chapter Three, Endocannabinoid Receptor Genetics and Marijuana Use, editor and chapter by Emmanuel S. Onaivi, et al., (pages 72-73, 91, and 333), Chapter 15, Neuropsychiatry: Schizophrenia, Depression, and Anxiety, chapter by Ester Fride and Ethan Russo, (page 378), (I.10.Endocannabinoids: FullText pdf)
  11. (I.11.sciencedaily) Genetic risk factor for binge eating discovered. Sciencedaily.com, Oct. 26, 2016,  https://www.sciencedaily.com/releases/2016/10/161026170543.htm (I.sciencedaily)
  12. (I.12.ncbi.FragileX) Sabiha Abekhoukh and Barbara Bardoni, CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome, Front Cell Neurosci. 2014; 8: 81., ncbi.nlm.nih.gov https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973919/ (I.ncbi.FragileX)
  13. (I.13.reuters) Pathway Maps: G-protein signaling_RAC1 in cellular process, Life Sciences Research, thomsonreuters.com, http://lsresearch.thomsonreuters.com/maps/383 (I.reuters)
  14. (I.14.genecards.CYFIP2) CYFIP2, genecards.org,  http://www.genecards.org/cgi-bin/carddisp.pl?gene=CYFIP2 (I.genecards.CYFIP2)
  15. (I.15.omicsgroup) Shahla Mohamadirizi1*, Vahid Shaygannejad2, Soheila Mohamadirizi3 and Marjan Mohamadirizi4, Eating disorders in a multiple sclerosis clinical population and its association with social anxiety.   https://www.omicsgroup.org/journals/eating-disorders-in-a-multiple-sclerosis-clinical-population-and-its-associationwith-social-anxiety-2376-0389-1000183.php?aid=82623 (I.omicsgroup)
  16. (I.16.sphingolipids)
  17. (I17..mpcfaculty.lipids)
  18. (I.18.coconut) Handbook of Plant-Based Fermented Food and Beverage Technology, Second Edition, edited by Y. H. Hui, E. Özgül Evranuz  CRC Press, May 17, 2012, https://books.google.com/books?id=5fvRBQAAQBAJ&pg=PA669&lpg=PA669&dq=sphingolipids+in+coconut&source=bl&ots=QlgC46XLn8&sig=Y5AiDM4oUTBp9BS3aOKCtWK0Fbk&hl=en&sa=X&ved=0ahUKEwiQuL-wmdbVAhUG7CYKHXZCCxsQ6AEILjAB#v=onepage&q=sphingolipids%20in%20coconut&f=false
  19. (I.19.BMHT.MS) Naveen Kumar Singhal, et al., Changes in Methionine Metabolism and Histone H3 Trimethylation Are Linked to Mitochondrial Defects in Multiple Sclerosis. J of Neuroscience Vol 35, Issue 45, 2015 PAGES: 15170-15186 ISSN: 0270-6474 https://www.researchgate.net/profile/Rohan_Dassanayake2/publication/283710653_Changes_in_Methionine_Metabolism_and_Histone_H3_Trimethylation_Are_Linked_to_Mitochondrial_Defects_in_Multiple_Sclerosis/links/5693c64508aeab58a9a2aaf3.pdf (I.BMHT.MS)
  20. (I.20.wikigenes)
  21. ( methionine )
  22. ( Dimethylglycine (DMG).
  23. John Bartlett, Familiar Quotations, 14th Ed., 1910, (p 634, I.23)
  24. (I.24.AMA resolution) American Medical Association Medical Student Section, Resolution 2, JUne 8, 2008, http://www.oregon.gov/pharmacy/Imports/Marijuana/Public/AMA_MedStudentSectionResolution.pdf (I.AMA resolution)
  25. (I.25.veteransformedicalmarijuana) AMA Votes to Reschedule Medical Marijuana, VMCA, http://www.veteransformedicalmarijuana.org/node/67 (I.veteransformedicalmarijuana)
  26. (I.26.fastcompany) Chris Dannen, Three Beginner Mistakes to Avoid When Eating Cannabis, fastcompany.com Sept. 10, 2014, https://www.fastcompany.com/3035175/three-beginner-mistakes-to-avoid-when-eating-cannabis (I.fastcompany)
  27. (I.27.jotopr) Karen Barth, New Study Shows Women are Hit the Hardest as Opioid Epidemic Sweeps the Country. Jotopr.com, Feb. 27, 2017, https://jotopr.com/new-study-shows-women-are-hit-hardest-as-opioid-epidemic-sweeps-the-country/?utm_source=ReviveOldPost&utm_medium=social&utm_campaign=ReviveOldPost (I.jotopr)
  28. (I.28.npr) Shefali Luthra, After Medical Marijuana Legalized, Medicare Prescriptions Drop for Many Drugs. npr.org, July 6, 2016, http://www.npr.org/sections/health-shots/2016/07/06/484977159/after-medical-marijuana-legalized-medicare-prescriptions-drop-for-many-drugs (I.npr)
  29. Reuters, Legalized Marijuana Could Help Curb the Opioid Epidemic, Study Finds. March 27, 2017,nbcnews.com,  http://www.nbcnews.com/health/health-news/legalized-marijuana-could-help-curb-opioid-epidemic-study-finds-n739301 (I.29.nbcnews)
  30. National Helpline: Substance Abuse and Mental Health Services Administration: 1-800-662-HELP (4357), (1.30samhsa.org)
  31. Rape, Abuse and Incest National Network, RAINN Hotline: 1-800-656-HOPE, (1.31RAINN.)
  32. U.S. National Suicide Prevention Hotline:  1-800-273-8255, (1.32.suicidepreventionlifeline.org)
  33. Amy Yasko, Nutrigenomic Testing, Holistic Health International, http://www.holisticheal.com/health-tests/nutrigenomic-testing (I.33.Nutrigenomic Screening)
  34. Amy Yasko, Methylation Analysis Pathway: John Doe, Neurological Research Institute, http://www.holisticheal.com/media/wysiwyg/John_Doe_MPA_05.19.17.pdf (p22, I.34.example of the genetic screening I had)

A walk in the woods may help the microbiome and our mood

The microbiome is our own inner forest of beneficial and harmful microbes. Bacteria, yeasts and other types of microscopic organisms live within our gastrointestinal tract and on our other body surfaces. Beneficial bacteria help protect us from less helpful bacteria and yeast and other fungi. The moisture rich air of a forest has been found to have a variety of beneficial nutrients and may even provide some beneficial bacteria. [1]

Moisture rich air also can provide a positive lift for the mood from negatively charged ions. The smell of ozone in the air may be noticeable after a thunder storm or on the beach of a large lake or ocean. In excess ozone can cause headaches but smaller amounts may have a positive affect on the mood. [1]

Forest greenery, healthy and soothing for the mind.

Other research has found that simply looking at images of nature helped reduce stress levels for the study participants. Walking through urban areas has not been found to have as much stress reduction benefits as a similar amount of time spent walking through a more natural setting. [2]

Decorating indoor and outdoor settings in urban areas with images of nature may provide health benefits for residents and workers and have a positive affect on their mood.  [2 ,8]

Some types of indoor plants may provide additional benefits besides stress reduction or lift the mood. Some species of common indoor houseplants also help clean the air of chemicals commonly found in modern environments which may have negative effects on health. Volatile chemicals are released over time from plastics such as vinyl. New carpets and vinyl flooring may release larger amounts of volatile chemicals when they are first installed and continue to release smaller amounts over the years. Formaldehyde is one of the volatile chemicals which has been associated with health risks for adults and children and neurological risks for a developing fetus.

A study by NASA regarding what types of plants might help remove the negative chemicals found in the air of enclosed buildings led to a list of 50 houseplants that are effective at cleaning the air of negative chemicals. The complete list is available in a book and the top ten are listed online. The book goes into more detail about which plants may be better for removing which types of chemicals from the air of enclosed spaces – such as NASA spaceship. [3]

Volatile chemicals that can make an indoor environment more hazardous to breathe and which led to the term “sick building syndrome” include “formaldehyde, Volatile Organic Compounds (benzene and trichloroethylene or TCE), airborne biological pollutants, carbon monoxide and nitrogen oxides, pesticides and disinfectants (phenols), and radon.”  [3]

The book by Dr. B.C. Wolverton, the scientist who did the research for NASA, is called “How to Grow Fresh Air – 50 Houseplants that Purify Your Home or Office.” It includes more detail about which plants may be better for cleaning which types of chemicals from the air and includes basic guidance on the type of care and ease of care that each species of plant might require to keep it alive. [4]

Caution is needed to not over-water houseplants or to leave them in a poorly drained pot as it may lead to mold. Some types of mold can have negative health risks but the type common to a houseplant are more likely to simply smell musty which can have a negative impact on the air of an enclosed space.

Houseplants which require misting such as ferns may also be increasing the amount negatively charged ions of water in the air which may help promote positive moods for people in the room. Small electronic model waterfalls also can increase the amount of negatively charged water ions in the air. Some types of air purifiers include an ozone generator however they aren’t recommended by the EPA as too much ozone can have negative health consequences. [5]

An early indicator of too much ozone might be a headache. The ozone generating units may be useful for freshening the air of an enclosed space when there are no pets or humans in the room.  Levels of ozone necessary to kill “biological organisms” (such as mold spores perhaps) would also be irritating or harmful for humans to breath for very long however but can make a difference when used in an empty enclosed space at a higher setting, [5], and once the ozone generating machine is turned off the increased levels of ozone return to normal after a few hours in my personal experience and the room can be safely used again. Roughly — the ozone chemically clumps with other particles in the air, deodorizing and causing the heavy clusters to fall from the air and can be removed by vacuuming or mopping the floor.

I have used one of the ozone air cleaners in my home and it could cause obvious increases in ozone smell if turned up to full generating potential and that could lead to a headache for me. At lower power levels the ozone generation did seem to help freshen the air and it did seem to have a positive effect on my mood. * This information is provided not as a recommendation rather as a caution. The ozone generating air cleaners can be useful but can also be dangerous.

Electricity exists in many forms — in laptops and in a misty morning breeze.

For more time later – oxidative stress can be caused by lack of oxygen or too much, or emotional and other physical reasons [6] and it may be involved in how ozone could have positive effects at low levels and negative effects at increased levels. [7]

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

  1. Kelly Tatera, “Scientists Reveal Why “Forest Bathing” or Going to the Beach Boosts Our Well-Being,” Feb. 3, 2016 [1]
  2.  Jared Green, “Research Shows Nature Helps with Stress,” 9/8/2011 [2]
  3. Greg Seaman, “The Top 10 Plants for Removing Indoor Toxins,” May 13, 2009 [3]
  4. B. C. Wolverton, “How to Grow Fresh Air: 50 House Plants that Purify Your Home or Office Paperback,” April 1, 1997  [4]
  5.  U.S. Environmental Protection Agency, Indoor Air Quality (IAQ),Ozone Generators that are Sold as Air Cleaners” [5]
  6. Samima Selim, Oxidative Stress and Psychological Disorders, Curr Neuropharmacol. 2014 Mar; 12(2): 140–147.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964745/ [6]
  7. Masru Sagai, Velio Bocci, Mechanisms of Action Involved in Ozone Therapy: Is healing induced via a mild oxidative stress?, Med Gas Res. 2011; 1: 29. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298518/ [7]
  8. Byoung-Suk Kweon, Roger S. Ulrich, Verrick D. Walker and Louis G. Tassinary, Anger and Stress: The Role of Landscape Posters in an Office Setting, Environment and Behavior 2008 40: 355  https://www.researchgate.net/profile/Louis_Tassinary/publication/258132363_Anger_and_Stress_The_Role_of_Landscape_Posters_in_an_Office_Setting/links/0a85e5304d07b6d045000000.pdf [8]

Increase in electromagnetic radiation may be associated with increased autism

A graph showing a similar rate of increase in electromagnetic radiation exposure and increased rates of autism can be seen around 42 minutes in the following video, Dr. Erica Mallery-Blythe – Electromagnetic Radiation, Health and Children 2014:

This type of radiation can be from wireless cell phones or laptops or from living very close, within a few miles, of high powered electric lines or power stations.

And even wirelessly connected toys might be harmful to children. [1, 2, 3] A computer or telephone that is not wireless, but is on an old-fashioned landline would not have the same level of electromagnetic radiation.

Tinfoil hats would only act as an antennae and possibly increase radiation absorption, however grounded metal foil might absorb the radiation rather than deflecting it and causing it simply to bounce around more. Water also absorbs this type of radiation which may be part of the reason electromagnetic radiation is dangerous to humans and other life forms – we are water based. [4]

A nonprofit organization of physicians who would like to increase awareness of electromagnetic hypersensitity has more information available on their website and an opportunity to join their group: http://phiremedical.org/tag/pdfs-for-electromagnetic-hypersensitivity/

I’ve filed this under both autism and calcium because EMF radiation can cause an increased flow of calcium into the interior of cells which can lead to overexcitement of the cell and may lead to cell death. People with hypersensitivity to electromagnetic radiation have measurable differences in their skin in response to exposure to EMF radiation compared to non hypersensitive people. An increase in mast cells may be part of the difference between the two groups.

See this video for more information, and/or a research article by the speaker regarding electrohypersensitivity, https://www.ncbi.nlm.nih.gov/pubmed/17178584:

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Chronic itch, ion channels, magnesium and calcium

Genetic differences in more than 70 genes have been associated with increased itchiness. [1] Calcium and serotonin levels may be involved in increased itch or arthritis pain signals being sent/perceived. [2] See the excerpts below:

Summary: Too much or too little calcium and magnesium can affect pain, itching, and mood. The minerals are both electrically active, and provide energy for ion channels which control the transport of messenger chemicals like serotonin across cell membranes – such as nerve cell membranes.

“For neurons to become excited, you need a receptor to communicate with an ion channel,” said Dr. Bautista. “We tried a variety of experiments and found that HTR7 communicates with the TRPA1 ion channel. Both receptors seem to be working together to mediate chronic itch.” “The researchers found more than 70 genes whose expression was higher in the more itch-sensitive mice. Of these, the gene for the HTR7 receptor was the most closely linked to itch. In fact, the HTR7 gene was twice as active in the itchiest mice compared to the least sensitive mice. ”  [1]

  1. An Itch You Just Can’t Scratch; NIH-funded study identifies proteins that may cause chronic itch (Oct. 27, 2015) http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_chronic_itch_10272015.htm
  2. Adam Horvath, et al., Transient receptor potential ankyrin 1 (TRPA1) receptor is involved in chronic arthritis: in vivo study using TRPA1-deficient mice, Arthritis Res Ther. 2016; 18: 6http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718022/          

    Excerpt: “TRPA1 is also directly stimulated by intracellular calcium [24] and a broad range of noxious endogenous oxidative products, such as 4-hydroxy-2-nonenal, hydrogen peroxide, hypochloride, hydrogen sulphide, 15-delta prostaglandin J2 [2528]. Furthermore, there are several exogenous irritants like mustard oil (allyl isothiocyanate: AITC) [29], cinnamaldehyde [30, 31], allicin [32, 33] and formalin [34] that are known to be potent agonists of TRPA1. Inflammatory mediators, such as bradykinin and serotonin, can sensitize this receptor and increase the responsiveness of the nerve endings [19, 35]. These findings suggest that TRPA1 may be involved in the development and maintenance of arthritic pain, but the precise mechanisms are still unknown.”

  3. Rs6295: The “Single” and “Self-Transcendent” Gene (5-HT1A Receptor) https://selfhacked.com/2015/07/23/rs6295-the-single-and-self-transcendent-gene-5-ht1a-receptor/Magnesium and Calcium increase the binding of serotonin to the 5HT1A receptors in the cortex (purkinje cells). (R)

  4. Bujalska M., et. al., Magnesium ions and opioid agonist activity in streptozotocin-induced hyperalgesia. Pharmacology. 2008;82(3):180-6.http://www.ncbi.nlm.nih.gov/pubmed/18701828

  5. That Really Does Make It Worse

    Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

World Autism Awareness Day; “Please teacher” video

It is World Autism Awareness Day and a video (follow the link in the Tweet) was shared of students with autism addressing their teachers about their differences. The person who shared it describes it as heart breaking and it is but it is also hopeful.

 

Recently I was reading a poem by someone with autism and it reminded me of me. It was describing a feeling of not fitting in with the normal types of people but not wanting to be lumped in with the type of people who couldn’t communicate at all:

High functioning people with autism might understand and listen and be interested but not be comfortable or able to speak their thoughts well. They might enjoy going to a party and just listening and smiling on the outskirts rather than chatting much but they could still be enjoying themselves in their own ways. I liked to water plants during social gatherings at a church where I was a member. I was part of the group and enjoyed saying hi’s briefly to people and it helped the plants and gave me something to do so it wouldn’t seem odd to not get into longer chats with people. I’m much better at talking about nutrition then about social chit-chat.

Some families have found that smartphones allow instant texting as a modern solution to conversation. The family talks and the person with autism listens and texts back to them in response. It can also be common for people with autism to communicate in snippets of quoted lyrics or other phrases – using other’s words to say what’s also on their mind.

The Legoland article reminded me of my favorite “amusement” museum. The City Museum in St. Louis, Missouri is full of decorations made from recycled materials built into mosaics and patterned walls. The museum is built within and on the grounds of a large multi-storied building that was a shoelace factory. Shoelaces are still made there and can be purchased. There are numerous imaginative landscapes that can be physically explored and played on and in and under and above – the place is a jungle and cavern and a maze and amazing – truly. If I could live anywhere on the planet that I wanted to, then it might be here: http://www.citymuseum.org/

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

A U.S. Congressman is seeking a DOJ investigation of glyphosate

The U.S. Congressman Ted Lieu has called for a Department of Justice investigation of the chemical glyphosate used in the herbicide Roundup. There may have been collusion by an EPA worker and Monsanto to suppress investigation of the chemical’s health risks. It has been labeled a likely carcinogen.

“New questions about the safety of Monsanto weed killer Roundup are deeply troubling. I worked on the glyphosate issue last term and I believe consumers should immediately stop using Roundup, whose core ingredient glyphosate has been labeled a likely carcinogen and has been linked to non-Hodgkin’s lymphoma by the International Agency for Research on Cancer. We need to find out if Monsanto or the Environmental Protection Agency misled the public.”

-U.S. Congressman Ted Lieu,  “US Congressman Calls for DOJ Investigation into EPA-Monsanto Glyphosate Collusion” Mar 17 2017 – by Sustainable Pulse

Read more: http://sustainablepulse.com/2017/03/17/us-congressman-calls-for-doj-investigation-into-epa-monsanto-glyphosate-collusion/#.WMv1yjvytPb

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

A TEDx talk about SPECT Scans and Psychiatric Diagnosis

Psychiatry is a field that relies on talking and questioning patients about their symptoms and lives for the purposes of diagnosis. A pioneer in the field has been using a method to scan the electrical activity of the brain for the purpose of more accurate diagnosis with the goal of providing more accurate treatments.

Dr. Amen shares his findings from 83,000 SPECT scans taken over many years of his clinical work helping individual patients improve their health and quality of life with individualized diagnosis and treatment recommendations. While his findings have helped many patients with a variety of conditions, autism spectrum disorders are not a primary focus of his work. The scans can help clarify diagnosis of ADHD and many other psychiatric conditions and may be helpful with autism disorders but that will likely require more time and more patients. It is a private clinic that expects payment to be paid in full at the time of the appointment. The fees may be able to be covered in part by your health insurance company but you would have to submit the bill and work with your insurance company yourself – and it may require preauthorization so check with them first if you hope for some reimbursement.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Mental health and nutrients; TEDx talk by Julia Rucklidge

A TEDx talk by Julia Rucklidge, PhD reviews the risks of long term psychiatric medications for the mental health of young people and the benefits found with supplementing with a wide variety of micronutrients.

Supplementation for a community that experienced trauma was found to reduce the frequency/severity of PTSD in the individuals of the community.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Neuropathy can be a cause of extreme tiredness

An underlying problem affecting a main nerve or affecting many nerves can be a cause of tingling and numbness in the hands or arms and legs. An increased feeling of heaviness of the arms or legs or feeling tired from just holding the arms up in the air may be due to problems with the nerves rather than weakness of the muscles. Autoimmune disease or some nutrient deficiencies (vitamin B12 deficiency most common) can be causes of neuropathy, or nerve damage. Other common causes are mentioned later.

Autoimmune disease itself can be very tiring and a cause of muscle cramps and diffuse chronic pain and it could make it very hard to cope with a physically demanding job. Some types of nerve damage can become permanent but may be reversible if caught early enough and the underlying causes are corrected. Vitamin B12 may be poorly absorbed by elderly people or for others with digestive problems; a monthly injection of B12, bypassing the digestive system, is a common treatment.  Dissolve in the mouth supplements of B12, cobalamin, are also used sucessfully by some people. In Parkinson’s Disease neuropathy has been seen and “perhaps we should be measuring MMA levels in these patients and treating with cobalamin supplementation to reduce MMA levels and prevent neuropathy.” [4]

Recognizing when tiredness is tiredness and when it is due to underlying nerve damage may be a step that can help prevent the nerve damage from becoming more permanent paralysis or numbness. Neuropathy can also affect gland or organ function as well as affecting motion and sensation. Poor coordination can become a problem with walking or with picking up and not dropping things because they just slipped from your fingers. Symptoms may also include feeling moments of burning or stabbing pain and bowel and bladder problems may include constipation or feeling unable to urinate. [1]

Neuropathy may affect approximately 24 million people in the United States. [1]

Neuropathy is more of a risk for people with diabetes, about 30% of the cases are associated with diabetes. Heavy alcohol use and traumatic injury can also be causes. And autoimmune celiac disease, hypothyroidism and other immune system diseases and viral infections sometimes can be a cause. Some types of antibiotics, radiation and chemotherapy treatments may cause neuropathy. Some cases of neuropathy are present at birth. [1]

Since celiac disease may be a cause of neuropathy trying a gluten free diet may be worth trying, (and hypothyroidism can also be a cause of neuropathy and for some people that may also be due to or made worse by gluten sensitivity problems).

Not overeating sugars and simple starches in general may help prevent neuropathy from developing by promoting more stable blood sugar. Elevated levels of blood sugar may be part of the cause of nerve damage which would be especially important for diabetics who are more at risk for elevated levels: [3].

Hot pepper – and it’s active ingredient capsaicin may be helpful. It is available over the counter as an active ingredient in skin ointments made for pain relief for arthritis patients and others with chronic pain. Warm showers or a bath may also help circulation and muscle relaxation. Taking care with toenail health is important as numbness becomes more extreme and minor injuries may become infected and go unnoticed until they become major infections and are more visibly discolored or swollen. [1]

Of the 16 million Americans with diabetes, approximately, about 25% have foot problems due to peripheral neuropathy.  Peripheral nerves are those extending out from the brain or spinal cord to the muscles and organs and skin. Neuropathy can progress from feeling tingling sensations of ‘pins and needles’ in the fingertips to not being able to feel sensations of hot, cold or pain. [2]

Peripheral neuropathy has been known to occur with Parkinson’s disease, possibly due to treatment with L-dopa [4], or possibly as a side effect with another commonly used treatment, dopamine hydrochloride. [5] Dopamine producing cells become dysfunctional in Parkinson’s Disease. [6] Dopamine is a brain neurostransmitter involved in movement but it is also has roles in immune system function.

Adequate levels of dopamine are involved in preventing both autoimmune disease and cancer. Research that compared the lifestyles of family members with and without Parkinson’s Disease found that siblings without the disease were more likely to have been coffee drinkers (three or more cups per day) and were more likely to have smoked tobacco cigarettes. Smoking tobacco has negative health risks but it may help boost dopamine levels and may have some protective effects on the dopamine producing cells. [7]

Smoking tobacco may have protective effects for some people but not others due to underlying differences in genetics. Coffee intake has also been associated with less risk of developing non-alcoholic fatty liver disease (NAFLD), [8] but again it may be helping those with a certain type of genetics and be a negative risk for people with other types of genes. Obesity and smoking cigarettes once a patient already has non-alcoholic fatty liver disease is associated with the disease getting progressively worse. [9] Fructose, sugar from fruit or refined in the form of high fructose corn syrup, intake has also been associated with worsening of NAFLD. [10] And non-alcoholic fatty liver disease has been associated with neuropathy risk in patients with diabetes. [15] So protecting the liver might be helping protect the nerves at the same time.

Protecting liver function may be important for protecting against cancer. The herb milk thistle has been found to have some protective affects for the liver. [12] Cirrhosis of the liver is also associated with peripheral neuropathy so protecting the liver may also help protect the nervous system and brain and help prevent neuropathy from developing. [11]

Summary of tips for protecting against neuropathy:

  1. Stable blood sugar and not developing diabetes may help protect the nerves.
  2. Regular exercise and stretching and warm baths or showers and massage and other methods for increasing circulation may help protect the nerves.
  3. Not eating excessively of fructose or simple sugars may help prevent damage caused by glycation of proteins; and by helping prevent obesity or diabetes.
  4. Moderate use of coffee may help protect the liver from non-alcoholic fatty liver disease and some types of liver disease have been associated with peripheral neuropathy.
  5. Dopamine or L-dopa when used as a medication to treat Parkinson’s Disease may be involved in development of peripheral neuropathy. Parkinson’s Disease involves dysfunctional production of dopamine so some other issue may be involved that causes peripheral neuropathy or it may be important to have adequate but not excessive levels of dopamine for health of the nerves.
  6. A deficiency of vitamin B12, also called cobalamin, can be non-reversible cause of peripheral neuropathy. [13]
  7. Smoking tobacco may have some protective affects against Parkinson’s Disease for some people but it has also been associated with worsening of non-alcoholic fatty liver disease in patients who already have the disease. It is unclear at this time what genes may be involved in why some people seem less at risk from tobacco smoking than others – overall it has been found to be associated with lung cancer. Chemicals within smoke cause blood vessels to constrict and reduces circulation. It has been associated with worsening of diabetic peripheral neuropathy so quitting smoking may be more protective of nerves. While it may help boost dopamine levels there are many other healthy ways to boost dopamine naturally. [14]
  8. Following a gluten free diet may be helpful in preventing peripheral neuropathy for some people. If hypothyroidism is also a problem then trying a strict gluten free diet may be beneficial as it may be a cause of autoimmune sensitivities. Eating less gluten in that case would still be exposing the body to the autoimmune ‘allergen’ so a trial of a gluten free diet may have to be very strict and last several months to six months before significant health benefits occur (in research on autoimmune celiac disease it took six months on a very strict gluten free diet in order for the levels of autoimmune antibodies against gluten to be reduced — and (potentially) the thyroid hormone which the gluten molecule resembles.)

More information about dopamine and cancer and natural ways to raise dopamine levels are included in the group of Tweets mentioned in this Tweet, click to view the information on that site:

 

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

  1. http://thelightmedia.com/posts/28389-neuropathy-12-ways-to-identify-and-manage-this-painful-disease
  2. http://www.foot.com/site/foot-conditions/neuropathy
  3. https://en.wikipedia.org/wiki/Glycation
  4. http://www.medscape.com/viewarticle/725699
  5. http://www.ehealthme.com/ds/dopamine%20hydrochloride/neuropathy%20peripheral/
  6. http://justneurology.com/
  7. https://www.newscientist.com/article/dn11568-do-coffee-and-cigarettes-protect-against-parkinsons/
  8. http://www.medicalnewstoday.com/articles/264995.php
  9. http://onlinelibrary.wiley.com/doi/10.1002/hep.23516/full
  10. https://www.sciencedaily.com/releases/2010/04/100427081044.htm
  11. http://www.medscape.com/viewarticle/460036
  12. http://umm.edu/health/medical/altmed/herb/milk-thistle
  13. http://www.webmd.com/a-to-z-guides/supplement-guide-vitamin-b12#1
  14. http://mentalhealthdaily.com/2015/04/17/how-to-increase-dopamine-levels/
  15. https://www.ncbi.nlm.nih.gov/pubmed/28254449