Treatments vs ‘a cure’ – flashback to 2020

Vitamin C and Intravenous Vitamin C/Thiamine therapy for cytokine storm are treatments that have a long history of safe and effective use. In early 2020 even vitamin C was getting discredited by the media and FDA as helpful and allowed treatments for Covid19. The post Treatments vs ‘a cure’ was a response to online bickering about there being no ‘cure’ for Covid19 – the implication being it is wrong to talk about how vitamin C can help then.

Vitamin C is an essential nutrient for vascular health and most everything else in a functioning body, indirectly if not directly.

Treatment is about providing all of the care a person needs when their health function is over stressed and possibly dysfunctional in some ways due to inflammation or infection effects. Treatment is well rounded to support various needs and reduce various symptoms.

Looking for a single ‘cure’ is a medical model viewpoint, based on the success of antibiotics, but also the success in early research days when finding and providing vitamin C was a fairly quick “cure” for scurvy – a deadly disease that was found to be “Vitamin C deficiency“. In that case the treatment was the cure. Vitamin D for rickets was also an early wonder cure that helped children grow up with straight and strong leg bones. Vitamin D fortification of milk and infant formula helped reverse that trend. Sadly scurvy is still occurring occasionally and medical professionals miss the diagnosis and simple cure – provide vitamin C.

Scurvy – severe vitamin C deficiency: “The modern doctor must keep this ancient disease in mind, as it presents insidiously with debilitating repercussions, particularly in older people who are at a higher risk. It is easily treatable once detected.” (1)

In the post Treatments vs ‘a cure’, I took a close look at a molecular docking study (3) that had grouped potential inhibitors for SARS-CoV-2 infection or replication into seven categories. I found that my selfcare treatments covered six of the seven categories, and citrus peel alone was potentially helping my infection selfcare in five of the seven ways. In total though I was using many items included in six of the seven categories. (3) SARS-CoV-2 can enter cells in many ways and spreads by exosomes – making many strategies necessary to block it or stop infected cells from remaining a latent infection.

The seven categories:

  1. PLpro inhibitors: “hesperidin and neohesperidin…might be the potential 3CLpro inhibitors and could probably be used for treating SARS-CoV-2.” (3) Citrus peel is a source of hesperidin and neohesperidin and vitamin C – L(+)-Ascorbic acid, quercetinoids, and other bioflavonoids like rutin. (13); Riboflavin-vitamin B2; Silybin – Milk Thistle; “epigallocatechin gallate, [EGCG]…exhibited high binding affinity to PLpro protein, suggesting the potential utility of these compounds in the treatment of SARS-CoV-2.” (3) EGCG – pomegranate peel and/or green tea. EGCG also acts as a zinc ionophore when zinc is available. (11); (–)- Rosmarinic acid – rosemary.
  2. 3C-like main protease (3CLpro) inhibitors: metabolite of riboflavin, Flavin mononucleotide, which a high dose vitamin B2 supplement might provide as the metabolite; Lutein – kale and other vegetables; and also hesperidin, neohesperidin, and rosmarinic acid.
  3. RNA-dependent RNA polymerase (RdRp) inhibitors: silybin – Milk Thistle.
  4. Helicase (Nsp13) inhibitors: hesperidin, neohesperidin and other flavonoids. “The natural products, such as many flavanoids from different sources (α-glucosyl hesperidin, hesperidin, rutin, quercetagetin 6-O-β-D-glucopyranoside and homovitexin), …showed high binding affinity to this target.” (3) Rutin is found in green and black tea and a few other foods. Quercetagetin… seems to be a form of quercetin, which also can act as a zinc ionophore, (11) and is in citrus and pomegranate peel and many plants. Homovitexin is also called isovitexin and is found in cannabis and flaxseed and in a few other foods. (4)
  5. Targets inhibiting virus structural proteins: hesperidin, and “licoflavonol from Glycyrrhiza uralensis” -non DGL licorice root. “By superimposing the ACE2–RBD complex to the hesperidin–RBD complex, a distinct overlap of hesperidin with the interface of ACE2 could be observed (Fig. 6C), suggesting hesperidin may disrupt the interaction of ACE2 with RBD [the RBD section of the SPIKE protein]. ” (3)
  6. Targets inhibiting virulence factor: did not include any that I was taking.
  7. Targets blocking host specific receptor or enzymesneohesperidin and hesperidin from Citrus aurantium again, the two phytonutrients are also in the peel of other citrus species. (5) “The natural products, such as phyllaemblicin G7 from Phyllanthus emblica, xanthones from the plants of Swertiagenus, neohesperidin and hesperidin from Citrus aurantium, exhibited potentially high binding affinity to ACE2 protein. ” (3

Hesperidin is in five of the seven categories; neohesperidin in four; and riboflavin, silybin and rosmarinic acid might help in two ways. Pomegranate peel phytonutrients likely also can help in numerous ways.

Treatments are needed for multifactorial problems, and SARS-CoV-2 or chimeric spike effects include multiple routes of possible harm. To ‘cure’ this – we need many treatments.

Disclaimer: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Reference List

  1. Callus CA, Vella S, Ferry P. Scurvy is Back. Nutr Metab Insights. 2018 Nov 21;11:1178638818809097. doi: 10.1177/1178638818809097. PMID: 30479485; PMCID: PMC6249652. https://pubmed.ncbi.nlm.nih.gov/30479485/
  2. J Depew, Treatments vs ‘a cure’, April 3, 2020, transcendingsquare.com, https://transcendingsquare.com/2020/04/03/treatments-vs-a-cure/
  3. Canrong Wu, Yang Liu, Yueying Yang, et al., Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods. Acta Pharmaceutica Sinica B, 27 February 2020, https://doi.org/10.1016/j.apsb.2020.02.008 https://www.sciencedirect.com/science/article/pii/S2211383520302999 * the genetic structure of the SARS-CoV(2) virus more closely matches the first, 2003, SARS-CoV virus in the way it can enter at ACE2 Receptors than it resembles the genetic structure of the coronavirus from bats native to China. There has also not been research support of the theory that the bat virus can infect humans as the shape does not fit the human ACE2 receptor: “…4 among the 5 most important amino acids (L465, L495, Y502, D510, and H514) that bind to ACE2 12 in Bat-CoV RaTG13 differ from SARS-CoV-2 (Fig. 3C). And there is no related research literature about whether Bat-CoV RaTG13 can infect human yet.”
  4. The other numbered references are on the original post. See 2 above. https://transcendingsquare.com/2020/04/03/treatments-vs-a-cure/

Falseness of research – JPA Ioannidis, 2015

Dr. Robert Malone more recently published an article summarizing how media and research have added to wrong information being spread and believed about Covid19.

Phil Harper, of The Digger Substack & new podcast, did an interview with Pierre Kory, MD, a doctor with the Frontline doctors working to help CoV patients. He uses Ivermectin successfully and discusses the difficulties and biased or false research that has been used to discredit use of a medication with a long and safe history – including a Nobel Prize. Towards the end of the interview he also points out that all effective treatments and dietary supports have been suppressed or discredited. He goes further to say it is a long history of the same fraud to support pharmaceuticals and suppression of effective low budget care. The suppression of side effects of psychiatric and other medications was also mentioned. To listen you do need to be a paid or free trial subscriber. (Phil Harper/Substack/The Digger)

John P.A. Ioannidis reviews research about bias and other effects that seem to do with competitiveness in a field of study – who will be first? Larger group numbers and larger effects tend to be more accurate than studies with small group size which found minimally significant effects. Financial interest in the outcome of the study also seems to impact reliability of the results of the funded research.

Why Most Published Research Findings Are False – Abstract, Summary

There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance.

Simulations show that for most study designs and settings, it is more likely for a research claim to be false than true. Moreover, for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias.

In this essay, I discuss the implications of these problems for the conduct and interpretation of research.

Citation: Ioannidis JPA (2005) Why Most Published Research Findings Are False. PLoS Med 2(8): e124. https://doi.org/10.1371/journal.pmed.0020124 https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020124

Published: August 30, 2005, Copyright: © 2005 John P. A. Ioannidis. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Meme shared by Dr. Malone recently in an email newsletter.

Regarding manipulation in media in Germany/Europe, a file from Wikileaks is in German, papers about or by Gunter Wallraff, German author and undercover journalist (en-academic.com): https://www.dropbox.com/s/bq3fet4izfq0y2s/wallraff-aufmacher-unzensiert.pdf?dl=0

Disclaimer: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

History of covert science by Nazi’s – Operation Paperclip & more recent AIDS/Ebola research.

Two videos are worth viewing and considering as a set – what does the early history have to do with the more recent history? Hard to know if names and histories of individual scientists was changed during Operation Paperclip.

See: Annie Jacobsen, “Operation Paperclip”, Politics and Prose, Youtube channel.

Annie Jacobsen, “Operation Paperclip”, Politics an Prose, Youtube.

See: Dr Horowitz, HiV and Ebola GOF history in US research: https://odysee.com/@deNutrients:0/DrHorowitz_HIVandEbola_GOF_history:0

Also of interest:

While a search for the quote “The modern media is a pastiche of sex and soft eroticism.” did not find the article, it did show there is a problem that people have noticed and written about. (variation of the search) Totalitarian takeover of a nation generally includes breaking down traditional family partnerships and increasing the exploitation and discrimination of females. See the post: Mass Psychosis and Totalitarian Takeover.

Fluoride being added to the public water was a strategy used in prisons in some places to increase docility and decrease sex drive. Moderately low iodine can cause approximately a 15 IQ point decrease in intelligence, which iodine supplements may improve unless it was since prenatal development. Low iodine also causes apathy, depression and fatigue.

I am not sure of the source, this is not the same missing 404 page link. I was searching for my series of screenshots of that article and found this one first.

While I didn’t find that article either, Can the Dumbing Down of America be Traced to Fluoridation? (thepanelist.net) is on a similar topic from a more academic perspective. From a dietitian perspective the answer is a strong “Yes“. We now have 3 and a half generations of US citizens born with a possible deficiency of iodine in ratio to the competitive halides in our water, food and medications: fluoride and bromide; and environmental perchlorates (low doses even can affect thyroid function, perchlorates).

Repetitive messaging, nutrient deficiencies, and modern toxins in the food supply and medications are all adding up to a public that is easily manipulated for the purpose of control by some covert internationally linked group.

At some point when the evidence suggests that killers are in charge, it would make sense to stop cooperating with being slowly and painfully maimed and killed. It appears that the US lost WWII by being infiltrated in advance. Related post: Against Our Better Judgement, a book summary.

Disclaimer: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

FDA approves CoV injection EUA for infants and children

Children are being harmed already. The EUA for children will remove liability risk for adult use of a vak product.

A comment to the FDA board, https://rumble.com/embed/v15yv60/?pub=4

Normal channels are compromised. Expecting reason or respect for human rights from the people in charge of this is not working. Citizens’ arrests are needed of all in charge, all involved, and quickly, before more children are maimed or killed.

Children make up a small percent of all people in total, and of all who have received CoV injections. And the percent of children who died of CoV makes up an even smaller percent of total.

This has never been an infection emergency for children. Lockdown, masking, the changes in society, those have been harmful to children.

Graphics via John Cullen, https://twitter.com/I_Am_JohnCullen/status/1537067362561961984?t=sPTL91yUG5qEFvv5WLBwqQ&s=19

Disclaimer: information is being shared for the purpose of education within the guidelines of Fair Use.