Falseness of research – JPA Ioannidis, 2015

Dr. Robert Malone more recently published an article summarizing how media and research have added to wrong information being spread and believed about Covid19.

Phil Harper, of The Digger Substack & new podcast, did an interview with Pierre Kory, MD, a doctor with the Frontline doctors working to help CoV patients. He uses Ivermectin successfully and discusses the difficulties and biased or false research that has been used to discredit use of a medication with a long and safe history – including a Nobel Prize. Towards the end of the interview he also points out that all effective treatments and dietary supports have been suppressed or discredited. He goes further to say it is a long history of the same fraud to support pharmaceuticals and suppression of effective low budget care. The suppression of side effects of psychiatric and other medications was also mentioned. To listen you do need to be a paid or free trial subscriber. (Phil Harper/Substack/The Digger)

John P.A. Ioannidis reviews research about bias and other effects that seem to do with competitiveness in a field of study – who will be first? Larger group numbers and larger effects tend to be more accurate than studies with small group size which found minimally significant effects. Financial interest in the outcome of the study also seems to impact reliability of the results of the funded research.

Why Most Published Research Findings Are False – Abstract, Summary

There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance.

Simulations show that for most study designs and settings, it is more likely for a research claim to be false than true. Moreover, for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias.

In this essay, I discuss the implications of these problems for the conduct and interpretation of research.

Citation: Ioannidis JPA (2005) Why Most Published Research Findings Are False. PLoS Med 2(8): e124. https://doi.org/10.1371/journal.pmed.0020124 https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020124

Published: August 30, 2005, Copyright: © 2005 John P. A. Ioannidis. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Meme shared by Dr. Malone recently in an email newsletter.

Regarding manipulation in media in Germany/Europe, a file from Wikileaks is in German, papers about or by Gunter Wallraff, German author and undercover journalist (en-academic.com): https://www.dropbox.com/s/bq3fet4izfq0y2s/wallraff-aufmacher-unzensiert.pdf?dl=0

Disclaimer: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

History of covert science by Nazi’s – Operation Paperclip & more recent AIDS/Ebola research.

Two videos are worth viewing and considering as a set – what does the early history have to do with the more recent history? Hard to know if names and histories of individual scientists was changed during Operation Paperclip.

See: Annie Jacobsen, “Operation Paperclip”, Politics and Prose, Youtube channel.

Annie Jacobsen, “Operation Paperclip”, Politics an Prose, Youtube.

See: Dr Horowitz, HiV and Ebola GOF history in US research: https://odysee.com/@deNutrients:0/DrHorowitz_HIVandEbola_GOF_history:0

Also of interest:

While a search for the quote “The modern media is a pastiche of sex and soft eroticism.” did not find the article, it did show there is a problem that people have noticed and written about. (variation of the search) Totalitarian takeover of a nation generally includes breaking down traditional family partnerships and increasing the exploitation and discrimination of females. See the post: Mass Psychosis and Totalitarian Takeover.

Fluoride being added to the public water was a strategy used in prisons in some places to increase docility and decrease sex drive. Moderately low iodine can cause approximately a 15 IQ point decrease in intelligence, which iodine supplements may improve unless it was since prenatal development. Low iodine also causes apathy, depression and fatigue.

I am not sure of the source, this is not the same missing 404 page link. I was searching for my series of screenshots of that article and found this one first.

While I didn’t find that article either, Can the Dumbing Down of America be Traced to Fluoridation? (thepanelist.net) is on a similar topic from a more academic perspective. From a dietitian perspective the answer is a strong “Yes“. We now have 3 and a half generations of US citizens born with a possible deficiency of iodine in ratio to the competitive halides in our water, food and medications: fluoride and bromide; and environmental perchlorates (low doses even can affect thyroid function, perchlorates).

Repetitive messaging, nutrient deficiencies, and modern toxins in the food supply and medications are all adding up to a public that is easily manipulated for the purpose of control by some covert internationally linked group.

At some point when the evidence suggests that killers are in charge, it would make sense to stop cooperating with being slowly and painfully maimed and killed. It appears that the US lost WWII by being infiltrated in advance. Related post: Against Our Better Judgement, a book summary.

Disclaimer: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

FDA approves CoV injection EUA for infants and children

Children are being harmed already. The EUA for children will remove liability risk for adult use of a vak product.

A comment to the FDA board, https://rumble.com/embed/v15yv60/?pub=4

Normal channels are compromised. Expecting reason or respect for human rights from the people in charge of this is not working. Citizens’ arrests are needed of all in charge, all involved, and quickly, before more children are maimed or killed.

Children make up a small percent of all people in total, and of all who have received CoV injections. And the percent of children who died of CoV makes up an even smaller percent of total.

This has never been an infection emergency for children. Lockdown, masking, the changes in society, those have been harmful to children.

Graphics via John Cullen, https://twitter.com/I_Am_JohnCullen/status/1537067362561961984?t=sPTL91yUG5qEFvv5WLBwqQ&s=19

Disclaimer: information is being shared for the purpose of education within the guidelines of Fair Use.

Marburg, WHO, and Facial Recognition/Digital ID

A video to watch:

Please share- we need as many as possible to be aware of this- Digital ID or Digital Prison- Presentation by Aman Jabbi. Live streamed to Central Coast community NSW on 2nd June 2022. Video post on Facebook.

Aman was at the forefront of video and camera technology in Silicon Valley. He has co-founded two camera startups. If you have a camera in your phone, stream video or movies, he played a part in it. Aman has a BS in Electrical & Electronics Engineering and MS in Chemistry from BITS in India, an MS in Electrical Engineering from Penn State University and studied Computer Science at Stanford University.

Have a listen to hear more about the smart cities infrastructure and implications, as its planned to descend upon us sometime soon! Newcastle is named as one of the first trial smart cities in Australia. You’ll also hear concepts such as: stakeholder capitalism, 4th Industrial revolution, digital real estate, the metaverse, lock down matrix, carbon credits, social credit score, facial recognition technology, public private partnership- all the concepts discussed by the WEF technocrats at Davos 22-26th May 2022.

Highlights from the video – a plan that may be underway – speculatively –

  • Step 1. The injections may contain preplanned future epidemics with pathogenic infections that can be triggered by certain EMF frequencies – 5G or other. Marburg hemorrhagic fever may be on the way.
  • Step 2. Use the ‘epidemic’ to increase WHO or other international control of individual nations.
  • Step 3. Increase control of citizens through digital ID and social credit system using facial recognition or other biotech.

Marburg virus – a rare but potentially deadly filovirus that causes hemorrhagic fever similar to Ebola. The family of filovirus also includes the less deadly Herpes virus.

Phytonutrients that may help against Marburg or similar virus include Melissa officinalis extract, (1), Ellagic acid from Rhodiola rosea, (2), and pomegranate whole fruit/peel extract. Pomegranate peel is also an excellent source of ellagic and gallic acid, and punicalagin, which are related to catechins. (4)

Extract of Rhodiola rosea displayed specific and potent inhibition against cell entry of both Ebola virus and Marburg virus. In addition, twenty commercial compounds that were isolated from Rhodiola rosea were evaluated using the pseudotyped Ebola virus entry assay, and it was found that ellagic acid and gallic acid, which are two structurally related compounds, are the most effective ones.” (2)

Of the five best chemicals for binding with SARS-CoV RBD spike domain – two are found in pomegranate – punicalagin and Epigallocatechin, gallate: “(A) Glycyrrhizin, [licorice root] (B) Nepritin, [3], (C) Punicalagin, (D) Epigallocatechin, gallate [EGCG], and (E) Theaflavin, [extract from black tea, also related to catechins (6)].” (5)

The catechins and gallic acid group include EGCG from green tea and pomegranate. The whole fruit extract of pomegranate or peel extract is a potent anti-microbial and anti-inflammatory, microbiome and immuno-modulator. It may also help with regeneration of hippocampal cells.

EGCG is a polyphenol in green tea and in the peel of pomegranates. It has been found to help regrow hippocampal cells which are the type that are damaged to the point of cell death in Alzheimer’s dementia:

Subsequently, another investigation demonstrated that administration of EGCG in adult hippocampal neural progenitor cell (NPC) cultures and in denate gyrus of adult mice improved spatial cognition thereby promoting adult neurogenesis. … [732]. ” (7)

Pomegranate or tea catechins may help reduce age related degeneration by promoting beneficial epigenetic changes. (8, 9)

Pomegranate can help inhibit mast cells which helps reduce a variety of inflammatory conditions including seasonal allergies and potentially long term risk of Alzheimer’s dementia.

Regarding mast cells and pomegranate extract: “Pomegranate extract (POMx) inhibits inflammation from activated human mast cells involved with connective tissue destruction and proteolytic activity associated with cartilage destruction, providing potential benefit for treating inflammatory diseases in which mast cells play an active role (Zafar et al. 2009).” (61)

For the Reference (61) and more information, see the document: Misfolded Proteins, H1 and NMDA Receptors, or Substack post: Hyperinflammation – A positive feedback loop leading to Alzheimer’s?.

Hyperinflammation, a positive feedback loop. Stress leads to NF-kB which inhibits Nrf2, which we need for cell and mitochondria maintenance.
Modern Life – Promoting NF-kB.
Is hyperinflammation a causal factor in Alzheimer’s dementia? Is the misfolded protein accumulation a result of increased inflammatory white blood cell activity rather than the cause? Allergy or autoimmune damage within the brain?

Disclaimer: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Reference List

  1. Methods of using extracts of melissa officinalis against filoviruses. US Patent: US10293012B2. 2019-05-21 https://patents.google.com/patent/US10293012B2/en
  2. Cui Q, Du R, Anantpadma M, Schafer A, Hou L, Tian J, Davey RA, Cheng H, Rong L. Identification of Ellagic Acid from Plant Rhodiola rosea L. as an Anti-Ebola Virus Entry Inhibitor. Viruses. 2018 Mar 27;10(4):152. doi: 10.3390/v10040152. PMID: 29584652; PMCID: PMC5923446. https://pubmed.ncbi.nlm.nih.gov/29584652/
  3. Agarwal OP. The anti-inflammatory action of nepitrin, a flavonoid. Agents Actions. 1982 Jul;12(3):298-302. doi: 10.1007/BF01965393. PMID: 6982607. https://pubmed.ncbi.nlm.nih.gov/6982607/
  4. Zahin M, Ahmad I, Gupta RC, Aqil F. Punicalagin and ellagic acid demonstrate antimutagenic activity and inhibition of benzo[a]pyrene induced DNA adducts. Biomed Res Int. 2014;2014:467465. doi: 10.1155/2014/467465. Epub 2014 May 14. PMID: 24949451; PMCID: PMC4052943. https://pubmed.ncbi.nlm.nih.gov/24949451/
  5. Mathew S, Benslimane F, Althani AA, Yassine HM, Identification of potential natural inhibitors of the receptor-binding domain of the SARS-CoV-2 spike protein using a computational docking approach.  Qatar Medical Journal, Vol 2021, Issue 1, March 12, 2021 https://www.qscience.com/content/journals/10.5339/qmj.2021.12?utm_source=TrendMD&utm_medium=cpc&utm_campaign=Qatar_Medical_Journal_TrendMD_1
  6. Leung LK, Su Y, Chen R, Zhang Z, Huang Y, Chen ZY. Theaflavins in black tea and catechins in green tea are equally effective antioxidants. J Nutr. 2001 Sep;131(9):2248-51. doi: 10.1093/jn/131.9.2248. PMID: 11533262. https://pubmed.ncbi.nlm.nih.gov/11533262/
  7. Itika Arora, Manvi Sharma, Liou Y. Sun,Trygve O. Tollefsbol, The Epigenetic Link between Polyphenols, Aging and Age-Related Diseases. Genes 2020, 11(9), 1094; https://doi.org/10.3390/genes11091094 https://www.mdpi.com/2073-4425/11/9/1094/htm
  8. Long-term dietary flavonoid intake and risk of Alzheimer disease and related dementias in the Framingham Offspring Cohort. 22 April 2020 https://academic.oup.com/ajcn/advance-article/doi/10.1093/ajcn/nqaa079/5823790
  9. Low Flavonoid Intake Associated with Alzheimer’s Risk. MedicalNewsToday.com  https://www.medicalnewstoday.com/articles/low-flavonoid-intake-associated-with-alzheimers-risk#6-types-of-flavonoid