The herbicide glyphosate is similar to glycine, an amino acid

The herbicide glyphosate was originally patented as an antibiotic and as a mineral chelator (a protein that can bind and transport minerals). It has been in use as an agricultural herbicide since 1975. However it’s use greatly increased in the last ten years since genetically modified Round-Up Ready crops were developed. A professor from Massachusetts Institute of Technology has been researching glyphosate and it’s possible role in the development of autism.

Professor Seneff gave two presentations at an Autism One conference earlier this year. The PowerPoint slides to the lectures are available in links included in the Tweets below, click these links for the pdfs to each video: people.csail.mit.edu/seneff/2016…

The first video includes more information about the chemical similarity between glyphosate and glycine. Glycine is an amino acid that provides methyl groups. Glyphosate is very similarly shaped but has an extra side chain and it wouldn’t provide methyl groups. It is possibly similarly shaped enough, however, for glyphosate to be incorporated into the structure of proteins instead of glycine. It would be like a puzzle piece that fits into another piece but won’t allow any other pieces to be added. Glyphosate may fit in glycine’s spot within a protein but then wouldn’t provide any methyl groups and the extra side chain could interfere with receptor function – like having an extension cord with prongs that no longer can fit into an electric socket because the socket is already blocked with something else.

The risk to health if this is true could be significant. Many proteins contain glycine and any one of them might be important in a variety of ways which glyphosate could disrupt. This is in very early stages of research but the impact could also affect vaccinations because the collagen used to culture material for vaccinations could contain glyphosate instead of glycine if the animals from which the collagen was obtained had been raised with feed containing glyphosate residue.

Zika virus that grew in an environment that contained glyphosate might have it incorporated into proteins instead of glycine which could be making the disease far more dangerous prenatally than it had been in past decades before glyphosate became widely used. Zika infections had not been associated with microcephaly until recently. The second video goes into more detail about how glyphosate could be making Zika more dangerous.

Professor Seneff explains in more detail about the glycine/glyphosate similarity in the first video:

I will get back to this topic after rewatching the videos and taking notes on the recommendations she makes about food and lifestyle strategies for reducing glyphosate exposure or reducing glyphosate levels that may be stored within the body.

9/20/2016 Update: See the following posts for more about glycine and glyphosate:

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

“Yes, autistic people do have feelings”; a link

According to one writer at least, “Yes, autistic people do have feelings.” Having difficulty understanding emotions can also leave a person with less skill when trying to communicate about their emotions. The linked article explains it better than I can try to re-explain, but it struck a familiar note with me.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

An organic food diet helped reduce pollutants for one family

In a short study a Swedish family who did not typically eat organic foods was monitored for 12 chemical pesticides that have recommended limits. The family of five people ate their typical non-organically grown food based diet for one week and then an organic food based diet for two weeks. Urine was monitored for the presence of the chemicals during the first and third weeks of the study. A video and news article about the study can be viewed here: http://www.mnn.com/food/healthy-eating/blogs/what-happens-when-you-switch-to-only-organic-foods.

The children in particular were found to have a decrease in the presence of pesticides during the organic food phase of the study. The total quantities of individual pesticides was not above recommended limits but with multiple chemicals all being present it is unclear what levels of the total amount of pesticide exposure might truly be safe. The youngest child had the highest level of any of the tested pesticides, chlormequat chloride (CCC) was elevated. The research discussion suggests the child may have had more servings of grains in proportion to the rest of her diet compared to the rest of the family and CCC is used in grain crops.

The results of the survey clearly show that some pesticides are absorbed into the body through diet. By choosing organic products, it is possible by and large to avoid the consumption of these chemicals through food. Compared with the period when the family consumed conventionally grown food, the concentrations of pesticide residues decreased on average by a factor of 6.7 when the family ate organic food. The children in particular had lower concentrations during the period of organic food consumption. Levels of most, but not all tested pesticides fell in the adults.                                                  Read more: https://www.coop.se/Vart–ansvar/Ekoeffekten/The-Organic-Effect/Read-the-report-from-IVL/

During the organic phase of the study the family also was asked to switch to organic household cleaning products and to not wear or buy brand new clothes or household items. The family had already been using environmentally friendly personal hygiene products prior to the study:

Other household products such as personal hygiene products, detergents, and new textiles may have contained the antibacterial agent triclocarban. When triclocarban degrades in the body, the metabolite 3,5-dichloroaniline (3,5-DCA) is formed, which is also a degradation product of pesticides (see Table 1). Consequently, it was important to take this form of exposure into account during the weeks when the family was consuming organic food so as to facilitate the evaluation of this study. Consequently, detergents were changed during the organic weeks. The family was also asked not to wear newly purchased clothing, bedding, or towels during this period. The father of the family uses snus, which was replaced with organic snus during the organic weeks. The family was already using environmentally friendly personal hygiene products such as shampoo, conditioner, and skin care products prior to the study.”                                                                     Read more: https://www.coop.se/Vart–ansvar/Ekoeffekten/The-Organic-Effect/Read-the-report-from-IVL/

Chemicals are throughout our environment but this study suggests that it may indeed be worth the effort to switch to more organic/environmentally friendly products.

The revolution our country needs is one against pollutants in our homes and bodies and in the landscape. A pesticide with chloride would likely to adding to a child’s risk of hypothyroid problems and symptoms such as excess weight gain and depression later in life. Our country’s and other countries’ increased rates of obesity could be related to pesticides that promote hypothyroidism or other metabolic changes that promote insulin resistance and increased risk of diabetes. The sooner we learn more about the health consequences of having a mixture of multiple pesticides and toxins, the sooner we can stop adding them to our environment. Most things are easier to apply than to remove.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Glyphosate was created as an antibiotic and mineral chelator but is being used as an herbicide

Every cell in our bodies depends on mitochondria to produce energy from stored sugar. Mitochondria are actually bacterial in origin. They are smaller than human cells and have their own DNA that is different from the the human cell DNA. Glyphosate is presumably safe for use in the human food supply because it only affects a metabolic pathway found in plants and bacteria however if every cell of our human bodies also depends on mitochondria which are bacterial in origin then is the antibiotic glyphosate truly safe for human use? Or for use in food for farm animals – which also depend on mitochondria to produce energy from sugar (glucose is the form of sugar that is broken down for energy within mitochondria).

A concerned scientist has been studying the topic for years and has been writing about the topic, read more: http://www.westonaprice.org/health-topics/roundup-the-nontoxic-chemical-that-may-be-destroying-our-health/   The topic is dangerous to write about however within the current business world which seems to be oriented to support corporate profit  over the long term viability of our ecosystem. The authors of that paper have been labeled ‘debunked’ or something similarly dismissive.

Glyphosate is being sprayed on invasive plants in wild areas and within waterways that are overgrown with invasive plants. However the affects of the antibiotic and mineral chelator on the desirable plants and wildlife is not known. A mineral chelator generally has been thought of as helpful, the phrase refers to chemicals that can bind onto a mineral and help transport it into cells or into the body from the gut. A mineral chelator that binds onto toxic minerals and helps transport them into the body might be not helpful or a mineral chelator that binds onto nutrients in the soil and prevents them from being absorbed by the plant would also be not helpful to the plant or possible to the humans or animals eating the plant.

Glyphosate was first patented as an antibiotic and as a mineral chelator before it was developed into an herbicide.

Glyphosate has been found in all samples of California wine that was tested in one study and it was found in over 40% of organically grown honey that was tested in another study and in over 60% of the commercially produced samples of honey. The chemical can be difficult and expensive to screen for using many of the typical methods however another method was used for screening the samples of honey:

The a1nalytical program included the extraction of glyphosate from the various matrices and the subsequent determination of glyphosate residues by enzyme linked immune sorbent assay (ELISA).” “(Figure 4) depicts the concentration of glyphosate in honey samples grouped by growing method of source pollen: organic (11 samples) and traditional (58 samples); 5 of the 11 organic samples had glyphosate concentrations above the method LOQ with a range of 26 to 93 ng/g and a mean of 50 ng /g. Of the fifty-eight non-organic honey samples, thirty-six samples, or sixty-two percent (62%), contained glyphosate concentrations above the method LOQ, with a range of 17 to 163 ppb and a mean of 66 ppb.

Read more: http://www.omicsonline.org/open-access/survey-of-glyphosate-residues-in-honey-corn-and-soy-products-2161-0525.1000249.php?aid=36354

Figure 5 includes data comparing samples of honey produced in countries that don’t allow GMO Round-Up Ready crops with samples from countries that do. Samples from countries that don’t allow GMO crops had an average of 31 ng /g of glyphosate compared to 71 ng/g of glyphosate found in the samples of honey produced in countries that do allow GMO crops.  “Although glyphosate is not acutely toxic to bees, it is chronically toxic to animals and is reported to disrupt the endocrine system [35,36] and a recent study indicates that honey bees exposed to increasing sub-lethal concentrations of glyphosate exhibit a decrease in acetyl cholinesterase (AChE) activity [37].” Further study is recommended in order to further assess whether glyphosate might be adding to the loss of bee hives that has been associated with use of neonicotinoid chemicals. Read more: http://www.omicsonline.org/open-access/survey-of-glyphosate-residues-in-honey-corn-and-soy-products-2161-0525.1000249.php?aid=36354

Fewer samples of wine produced in California were tested but 100% of the samples (n=10) were found to have glyphosate contaminants. The wine produced from grapes grown organically  did have less of the contaminant than the commercially produced wine. That may not help the people living in the areas where grapes are grown for the California wine: “According to the CA Dept of Health, breast cancer rates in the Sonoma, Napa and Mendocino counties is 10 to 20 percent higher than the national average.” “German scientists have shown that 0.1 ppb of glyphosate, which is patented as an antibiotic, has been shown to destroy the beneficial gut bacteria and promote the proliferation of pathogenic gut bacteria.(2)” “0.1ppt of glyphosate has also been shown to stimulate the growth of breast cancer cells.(3)” “Glyphosate has also been shown to increase antibiotic resistance, which could be leading to superbugs (9)” Read more:  https://d3n8a8pro7vhmx.cloudfront.net/yesmaam/pages/680/attachments/original/1458830087/GlyphosateContaminationinWinePressReport_(2).pdf?1458830087

So how much glyphosate might be too much? — Not much if 0.1 ppb is enough to destroy our beneficial gut bacteria and 0.1 ppt is enough to stimulate growth of breast cancer cells. And if it’s presence in the environment is increasing the risk of more pathogens developing antibiotic resistance than any of it might already have been too much for people with antibiotic resistant pneumonia.

And how much glyphosate might be deadly? — Twenty milliliters was not quite enough for at least one suicidal patient who did manage to make herself sick with a antibiotic resistant bacterial infection after ingesting the 20 ml of glyphosate in a suicide attempt (this is sad but is not uncommon – many people commit suicide by eating agricultural chemicals). (Twenty milliliters would be equal to about 4 teaspoons of glyphosate.) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289481/

How many ppb in one milliliter? –> search engine –>

“This is the same as grams per 1,000 liters, which may be converted to milligrams per liter (mg/L). Therefore, 1 g/ m3 = 1 mg/L = 1 ppm. Likewise, one milligram per cubic meter (mg/m3) is the same concentration in water as one microgram per liter (ug/L), which is about 1 ppb.”

So not much glyphosate is needed to cause negative health effects in humans and in the environment. It can break down quickly but may also take up to twenty years to completely break down. If excessive amounts of glyphosate are allowed to accumulate it may become difficult for normal seeds to be able to grow and genetic modification might be necessary for producing any viable crops in areas where glyphosate residue becomes prevalent (such as in any countries that allow GMO crops and use of glyphosate as a desiccant.)

How much might be too much in nature? One part per million (1 ppm) equivalent to what might be found in the environment of countries that use glyphosate was found to be enough of a dose to produce deformities in 60% of the tadpoles of a tree frog. “Jayawardena et al. (2010) found nearly 60% malformations in tadpoles of the tree frog Polypedates cruciger treated with an environmentally relevant concentration of 1 ppm Roundup.” The formulated product (glyphosate plus surfactants or other additives) was found to be more harmful to offspring than the glyphosate alone. How much is too much in our food supply? We don’t know for sure but we are beginning to know more about how much may be present in our food supply: “Residues of up to 17 mg/kg of glyphosate have been found in harvested soybean crops [10].

Back to the search engine –> “1 mg/kg = 1000 ppb” So –> “Residues of up to [17000 ppb or 17,000,000 ppm] of glyphosate have been found in harvested soybean crops.” Which seems like it would be enough to cause malformations in at least 60% of tree frog tadpoles if they were exposed to Round-Up Ready soy.

Maybe it is completely safe for everyone — except the 2% who are developing autism and the 5.3 million people living with Alzheimer’s Disease.  North Dakota has the highest rate of mortality due to Alzheimer’s Disease and Nevada has the lowest rate.  http://www.alzheimers.net/resources/alzheimers-statistics/

Most glyphosate used at harvest time is done on spring and durum wheat, and mostly in the northern tier States (North Dakota & Montana) and ...”  This article is debunking a different article about use of glyphosate as a desiccant – this article states that is actually a rare practice – except possibly in North Dakota and Montana. Read more:  http://weedcontrolfreaks.com/2014/11/glyphosate-use-in-wheat/

The search engine suggests that glyphosate has been used for invasive plant control in Nevada but did not turn up agricultural references. A study on use of glyphosate for helping establish native plants in an area with invasive plants. The glyphosate use on the invasives did help with getting the native plantings established instead. http://sfc.smallfarmcentral.com/dynamic_content/uploadfiles/152/Nevada.pdf

The search term results: https://www.google.com/search?q=use+of+glyphosate+in+Nevada&rlz=1C1CHWA_enUS600US600&oq=use+of+glyphosate+in+Nevada&aqs=chrome..69i57.4494j0j7&sourceid=chrome&ie=UTF-8

The search turned up a paper that has since been retracted after it was published due to some delay in the peer review process but the paper can still be viewed. It suggests there is a correlation between glyphosate use which causes an increased need for nitrogen based fertilizers because the glyphosate can affect soil bacteria that normally would make nitrogen more available so more nitrogen based fertilizer is required and which can lead to more nitrogen dioxide being released into the air which can affect ADHD risk and is also a gas involved in global warming. the paper turned up in my search terms because Nevada didn’t have some data that other states had made available. States with data available regarding glyphosate use between 2006-2009 suggest that Arizona and Utah used less than in previous years,

It took fifty years or so before corporate control of science regarding cancer risk and smoking was freely available to consumers and it has taken twenty or so years to reveal Exxon’s role in denying the impact of fossil fuel use on climate change. It may take a while to reveal that spraying an antibiotic and mineral chelator is bad for soil health and health of other life forms. In the mean time I will continue to try to avoid sources of Round-up. It may be the combination of the adjuvants/surfactants that are used with the glyphosate that makes it more of a risk for neurodegenerative harm such as autism or ADHD than studies with glyphosate alone have suggested or it may be the changes in nitrogen based fertilizer use as suggested by the (retracted) article on ADHD and Round-Up.

/Disclosure: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes./